Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.52 |
| ▸ | MMP1 | P03956 | 6/20 | 0.52 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583610 | 0.84 | MMP1 (0.54) | MMP13MMP1MMP9MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL7349934 | 0.80 | MMP1 (0.75) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7765009 | 0.80 | MMP1 (0.58) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL27560639 | 0.79 | MMP1 (0.49) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL27488462 | 0.78 | MMP9 (0.56) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7226992 | 0.76 | ITGB1 (0.50) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7226993 | 0.76 | ITGB1 (0.50) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL21035359 | 0.76 | MMP1 (0.52) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7683529 | 0.76 | MMP1 (0.56) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7683521 | 0.76 | MMP1 (0.56) | MMP13MMP1MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009004-A1 | NOVEL PIPERAZINE COMPOUND, AND USE THEREOF AS HCV POLYMERASE INHIBITOR | Japan Tobacco, Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |