Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.52 |
| ▸ | MMP13 | P45452 | 7/20 | 0.52 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | MMP7 | P09237 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035574 | 0.82 | MMP13 (0.53) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035593 | 0.81 | MMP1 (0.46) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL7765009 | 0.79 | MMP1 (0.58) | MMP1MMP13MMP9ADAM17MMP3 | |
| Hydrochloric Acid SCHEMBL7349934 | 0.79 | MMP1 (0.75) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035075 | 0.79 | MMP13 (0.45) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL27488462 | 0.77 | MMP9 (0.56) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035512 | 0.77 | MMP1 (0.47) | MMP1MMP13ADAM17ALDH1A1HTT | |
| SCHEMBL21035511 | 0.77 | MMP1 (0.47) | MMP1MMP13ADAM17ALDH1A1HTT | |
| SCHEMBL4581963 | 0.76 | MMP13 (0.52) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL27583610 | 0.76 | MMP1 (0.54) | MMP1MMP13MMP9ADAM17MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |