Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581906 | 0.86 | PTGS2 (0.47) | PTGS2PTGS1PTGER2GABRA1GABRG2 | |
| SCHEMBL4582575 | 0.84 | PTGS2 (0.51) | PTGS2PTGS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4584165 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL4583426 | 0.80 | PTGS2 (0.51) | PTGS2PTGS1MAPT | |
| SCHEMBL3617636 | 0.79 | PTGS2 (0.50) | PTGS2PTGS1PTGER2MAPTRAB9A | |
| SCHEMBL4583198 | 0.78 | PTGS2 (0.52) | PTGS2PTGS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4582396 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4583216 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL4583796 | 0.75 | PTGS2 (0.52) | PTGS2PTGS1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4581586 | 0.73 | PTGS2 (0.39) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |