Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582575 | 0.86 | PTGS2 (0.51) | PTGS2PTGS1MAPTKDM4ENPC1 | |
| SCHEMBL4583216 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1LPLLIPG | |
| SCHEMBL4583796 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1MAPTKDM4EALDH1A1 | |
| SCHEMBL3617636 | 0.80 | PTGS2 (0.50) | PTGS2PTGS1MAPTKDM4EALDH1A1 | |
| SCHEMBL4582348 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1MAPTKDM4ENPC1 | |
| SCHEMBL4607900 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1MAPTKDM4ENPC1 | |
| SCHEMBL2454166 | 0.76 | PTGS2 (0.72) | PTGS2PTGS1LPLLIPG | |
| SCHEMBL4583426 | 0.75 | PTGS2 (0.51) | PTGS2PTGS1MAPT | |
| SCHEMBL4581906 | 0.71 | PTGS2 (0.47) | PTGS2PTGS1MAPT | |
| SCHEMBL4582564 | 0.68 | PTGS2 (0.43) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |