Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583216 | 0.92 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL4583198 | 0.92 | PTGS2 (0.52) | PTGS2PTGS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4583249 | 0.84 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL3617636 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4582575 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1POLBNPC1RAB9A | |
| SCHEMBL4583426 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1MAPT | |
| SCHEMBL4582348 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1NPC1TSHRRAB9A | |
| SCHEMBL4583796 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1POLBSMN1; SMN2MAPT | |
| SCHEMBL1868853 | 0.75 | PTGS2 (0.46) | PTGS2PTGS1POLB | |
| SCHEMBL4582842 | 0.74 | PTGS2 (0.39) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |