Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591894 | 0.83 | PTGS2 (0.44) | PTGS2PTGS1PGR | |
| SCHEMBL4583198 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1MAPTALDH1A1KDM4E | |
| SCHEMBL2454166 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL4582575 | 0.78 | PTGS2 (0.51) | PTGS2PTGS1MAPTKMT2AALDH1A1 | |
| SCHEMBL4583216 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL4582348 | 0.75 | PTGS2 (0.47) | PTGS2PTGS1MAPTALDH1A1KDM4E | |
| SCHEMBL4607900 | 0.75 | PTGS2 (0.57) | PTGS2PTGS1MAPTMEN1KMT2A | |
| SCHEMBL3617636 | 0.74 | PTGS2 (0.50) | PTGS2PTGS1MAPTALDH1A1KDM4E | |
| SCHEMBL4583426 | 0.72 | PTGS2 (0.51) | PTGS2PTGS1MAPTMEN1KMT2A | |
| SCHEMBL2349582 | 0.71 | PTGS2 (0.49) | PTGS2PTGS1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |