SCHEMBL4582701

SCHEMBL4582701

Cc1ccc(-c2cccnc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.68
CYP3A4 P08684 3/20 0.68
ALDH1A1 P00352 2/20 0.68
CYP1A2 P05177 1/20 0.68
NPC1 O15118 1/20 0.65
RAB9A P51151 1/20 0.65
KIF11 P52732 1/20 0.62
TP53 P04637 1/20 0.59
NFKB1 P19838 1/20 0.59
NFKB2 Q00653 1/20 0.59
RELA Q04206 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
MKNK1 Q9BUB5 4/20 0.57
MKNK2 Q9HBH9 4/20 0.57
CYP11B2 P19099 1/20 0.57
KDR P35968 1/20 0.55
EPHB4 P54760 1/20 0.55
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260412 1.00 CYP2A6 (0.68) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL14780606 0.94 CYP2A6 (0.60) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL12339149 0.92 MKNK1 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL12339140 0.92 CYP2A6 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL9974949 0.90 CYP2A6 (0.56) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL19309597 0.90 CYP2A6 (0.56) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL21345924 0.89 CYP3A4 (0.57) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL21019112 0.89 NPC1 (0.54) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL26550669 0.89 CYP11B2 (0.71) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
Thiophene SCHEMBL28308365 0.89 NPC1 (0.54) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715861-A MOFs material containing pyridyl ligand and preparation method and application thereof 嘉兴学院 2023-09-08 CN claimed
CN-115368387-A Metal organic coordination compound of 5-methyl isophthalic acid mixed ligand and preparation method and application thereof 嘉兴学院 2022-11-22 CN claimed
EP-3122707-B1 METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-25 EP claimed
EP-1663204-B1 C-KIT MODULATORS AND METHODS OF USE EXELIXIS INC (US) 2014-05-07 EP claimed
US-20240244946-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-12030890-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12030890-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
WO-2024126322-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
EP-3845546-B1 COMPLEXES JOHNSON MATTHEY PLC (GB) 2024-06-19 EP disclosed
EP-3842421-B1 COMPLEXES JOHNSON MATTHEY PLC (GB) 2024-06-12 EP disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
EP-1268418-A1 PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS Applied Research Systems ARS Holding N.V. (AN) 2003-01-02 EP disclosed
WO-2002102799-A2 PYRROLIDINE OXADIAZOLE- AND THIADIAZOLE OXIME DERIVATIVES BEING OXYTOCIN RECEPTOR ANTAGONISTS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2002-12-27 WO disclosed
WO-2002074741-A1 PYRROLIDINE ESTER DERIVATIVES WITH OXYTOCIN MODULATING ACITVITY APPLIED RESEARCH SYSTEMS ARS HOLDING NV (AN) 2002-09-26 WO disclosed
WO-2001074769-A1 PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2001-10-11 WO disclosed
WO-2001072705-A1 PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2001-10-04 WO disclosed
EP-0470391-B1 Use of pyridines as perfume or aroma ingredients FIRMENICH & CIE (CH) 1995-08-23 EP disclosed
US-5298486-A Orange oils for orange juice or seafood flavors FIRMENICH S.A. (CH) 1994-03-29 US disclosed
US-4128651-A Bis-quaternary pyridinium-2-aldoxime salts and a process for their preparation MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240244946-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS GPX1, PER2, SOD1 CYP2A6 2160/4885CYP3A4 1109/4885ALDH1A1 10/4885
US-12030890-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures DDT, ESD, DBF4 CYP2A6 1256/4885CYP3A4 75/4885ALDH1A1 722/4885
US-20240244947-A1 ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS PER2, GPX1, SOD1 CYP2A6 2374/4885CYP3A4 1253/4885ALDH1A1 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.