Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268191 | 1.00 | FAAH (0.37) | FAAHMAPTGAAF13A1TGM2 | |
| SCHEMBL2339602 | 0.88 | MMP9 (0.43) | SMN1; SMN2NPC1RAB9ATP53GRIN2B | |
| SCHEMBL4583118 | 0.87 | SMN1; SMN2 (0.40) | CTSKSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL2338938 | 0.87 | SMN1; SMN2 (0.40) | CTSKSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL2682844 | 0.87 | GAA (0.41) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1037741 | 0.87 | NPC1 (0.39) | CTSKSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL2338996 | 0.83 | RORC (0.38) | F13A1TGM2TGM1CTSKSMN1; SMN2 | |
| SCHEMBL2339949 | 0.83 | PPARG (0.40) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL2344278 | 0.83 | NPC1 (0.41) | CTSKSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL2343217 | 0.81 | REN (0.39) | MAOAMAOBGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |