Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338938 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ACTSKCYP2C19 | |
| SCHEMBL2339602 | 0.92 | MMP9 (0.43) | SMN1; SMN2NPC1RAB9APDE4BGRIN2B | |
| SCHEMBL2344278 | 0.90 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9ACTSKMEN1 | |
| SCHEMBL3268191 | 0.87 | FAAH (0.37) | SMN1; SMN2NPC1RAB9ACTSKCYP2C19 | |
| SCHEMBL4583065 | 0.87 | FAAH (0.37) | SMN1; SMN2NPC1RAB9ACTSKCYP2C19 | |
| SCHEMBL2338996 | 0.87 | RORC (0.38) | SMN1; SMN2NPC1RAB9ACTSKCYP2C19 | |
| SCHEMBL1037741 | 0.87 | NPC1 (0.39) | SMN1; SMN2NPC1RAB9ACTSKMEN1 | |
| SCHEMBL2344642 | 0.85 | LMNA (0.34) | CTSKHTR2CHPGDGRIN2B | |
| SCHEMBL2684607 | 0.84 | — | — | |
| SCHEMBL2339949 | 0.83 | PPARG (0.40) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |