Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17326567 | 0.88 | PTGDR2 (0.50) | XDHSLC22A12PTGER1PTGDR2NPC1 | |
| SCHEMBL4585031 | 0.85 | TDP1 (0.45) | XDHPTGER1NPC1LMNAHPGD | |
| SCHEMBL21939124 | 0.83 | XDH (0.49) | XDHSLC22A12ADRB3ADRB1DHODH | |
| SCHEMBL4003834 | 0.82 | ALDH1A1 (0.46) | PTGER1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL4584625 | 0.82 | TSHR (0.60) | PTGDR2LMNAHPGDCFDKDM4E | |
| SCHEMBL4282168 | 0.79 | FOS (0.50) | XDHSLC22A12DHODHTP53ALDH1A1 | |
| SCHEMBL19684688 | 0.79 | PTPN11 (0.51) | NPC1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6049299 | 0.79 | PTGDR2 (0.44) | PTGDR2ALDH1A1CFDKDM4EGLA | |
| SCHEMBL25419937 | 0.79 | ADRB3 (0.47) | XDHSLC22A12ADRB3ADRB1DHODH | |
| SCHEMBL25421711 | 0.79 | ALDH1A1 (0.50) | XDHSLC22A12ADRB3ADRB1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100582088-C | Aminoalcohol derivatives | ASTELLAS PHARMA INC | 2010-01-20 | — | — | CN | disclosed |
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| CN-1906154-A | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2007-01-31 | — | — | CN | disclosed |
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |
| US-20050137236-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137236-A1 | Aminoalcohol derivatives | GPR39, PRMT9, CHRM2 | XDH 1932/4885SLC22A12 1676/4885ADRB3 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.