Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607900 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL2456618 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1EDNRA | |
| SCHEMBL4583796 | 0.79 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL4583198 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1LPLLIPG | |
| SCHEMBL4582575 | 0.75 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL2350613 | 0.75 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL7842927 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL2356409 | 0.74 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL3974343 | 0.74 | PTGS2 (0.58) | PTGS2PTGS1EDNRA | |
| SCHEMBL2348407 | 0.73 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958948-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1974608-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-10-01 | — | — | EP | disclosed |
| EP-1974608-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-10-01 | — | — | EP | disclosed |
| EP-1958948-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | PTGS2 577/4885PTGS1 1335/4885EDNRA 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.