SCHEMBL4584013

SCHEMBL4584013

CCCCC(CC)CN(CCc1ccccc1)C(=O)CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
CA12 O43570 4/20 0.47
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
CA4 P22748 3/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
F2 P00734 2/20 0.44
PLG P00747 1/20 0.44
PLAT P00750 1/20 0.44
PRSS1 P07477 1/20 0.44
F10 P00742 1/20 0.44
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308145 0.80 CNR2 (0.50) CA2LTB4R2PRSS1KMT2AMEN1
SCHEMBL15431229 0.78 OPRM1 (0.48)
SCHEMBL18531386 0.76 LMNA (0.45) CA2LTB4R2PRSS1KMT2AMEN1
SCHEMBL14229143 0.76 CA12 (0.57) ALOX5CA12CA1CA2CA4
SCHEMBL14229426 0.75 CA2 (0.46) CA12CA1CA2TDP1L3MBTL1
SCHEMBL14229416 0.75 CA2 (0.46) CA1CA2TDP1HTTL3MBTL1
SCHEMBL8435861 0.75 KCNH2 (0.45)
SCHEMBL18435551 0.75 ALOX5 (0.60) ALOX5CA12CA1CA2CA4
SCHEMBL9306882 0.74 ALDH1A1 (0.48) CA2LTB4R2PRSS1
SCHEMBL24786011 0.73 ALPI (0.45) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1911438-A2 Cosmetic composition containing a derivative of dibenzoylmethane and a arylalkyl amide or ester compound; method of photostabilising the derivative of dibenzoylmethane L'Oréal (FR) 2008-04-16 EP disclosed
EP-1911438-A2 Cosmetic composition containing a derivative of dibenzoylmethane and a arylalkyl amide or ester compound; method of photostabilising the derivative of dibenzoylmethane L'Oréal (FR) 2008-04-16 EP disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds TYR, DDT, AADAC ALOX5 2493/4885CA12 4393/4885CA1 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.