Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678101 | 0.87 | GABRA1 (0.48) | MAPTALDH1A1HTTESR1ESR2 | |
| SCHEMBL4584092 | 0.81 | TYR (0.41) | MAPTALDH1A1HTTSHBGESR1 | |
| SCHEMBL70958 | 0.79 | CA1 (0.55) | MAPTALDH1A1HTTESR1ESR2 | |
| SCHEMBL9745295 | 0.78 | ALOX5 (0.46) | MAPTHTTESR1ALOX5PTGS2 | |
| SCHEMBL10894181 | 0.78 | ALOX5 (0.46) | MAPTHTTESR1ALOX5PTGS2 | |
| SCHEMBL10894467 | 0.78 | ALOX5 (0.46) | MAPTHTTESR1ALOX5PTGS2 | |
| SCHEMBL20102183 | 0.78 | DHFR (0.43) | ALDH1A1HTTGABRA1GABRB2ALOX5 | |
| SCHEMBL10977917 | 0.76 | NR1H2 (0.44) | MAPTALDH1A1HTTSHBGESR1 | |
| SCHEMBL9749694 | 0.76 | CA1 (0.59) | MAPTALDH1A1SHBGESR1ESR2 | |
| SCHEMBL70083 | 0.76 | CYP3A4 (0.42) | ALDH1A1SHBGESR1ESR2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281570-A | Heat sensitive sheets | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0141096-A1 | Polyarylate compositions | GENERAL ELECTRIC COMPANY (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0133658-A2 | Flame retardant non-dripping polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |
| US-4490504-A | CONTAINING GLASS FIBERS, DIHYDRIC PHENOLS, AND THIUODIPHENOLS | GENERAL ELECTRIC COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4477647-A | FIREPROOF ENGINEERING THERMOPLASTICS | GENERAL ELECTRIC COMPANY (US) | 1984-10-16 | — | — | US | disclosed |