Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458444 | 1.00 | RET (0.32) | RETGRM4 | |
| SCHEMBL458009 | 0.85 | DPP4 (0.35) | RETGRM4 | |
| SCHEMBL458011 | 0.80 | ACACB (0.35) | RET | |
| SCHEMBL470601 | 0.79 | NTRK1 (0.38) | RETGRM4 | |
| SCHEMBL458443 | 0.78 | — | — | |
| SCHEMBL14730264 | 0.76 | HPGDS (0.38) | — | |
| SCHEMBL14730281 | 0.76 | MAOA (0.32) | RET | |
| SCHEMBL457627 | 0.75 | DPP4 (0.34) | RETGRM4 | |
| SCHEMBL470550 | 0.75 | DPP4 (0.35) | RETGRM4 | |
| SCHEMBL6128140 | 0.75 | GPR119 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |