SCHEMBL4584701

SCHEMBL4584701

C[Si](C)(C)C#Cc1ccc2c3ccccc3c3c(C#C[Si](C)(C)C)c(C#C[Si](C)(C)C)c(C#C[Si](C)(C)C)c(C#C[Si](C)(C)C)c3c2c1C#C[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718325 0.78 ALDH1A1 (0.31) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL20626280 0.77 KDM4E (0.33) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL20534467 0.74 CYP1A2 (0.41) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL30620185 0.74 CYP1A2 (0.41) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL28468438 0.74 KDM4E (0.36) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL1470735 0.72 ALDH1A1 (0.35) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL29690232 0.72 ALDH1A1 (0.35) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL12405322 0.71 KDM4E (0.39) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL3845195 0.70 KDM4E (0.41) KDM4EMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL15274205 0.68 L3MBTL1 (0.43) KDM4EMEN1ALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080265750-A1 Triphenylene Compounds, Method of Manufacturing the Same and Organic Electroluminescent Devices Employing the Same NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080265750-A1 Triphenylene Compounds, Method of Manufacturing the Same and Organic Electroluminescent Devices Employing the Same SMARCC2, SMARCC1, TERT KDM4E 975/4885MEN1 1293/4885ALDH1A1 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.