Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594366 | 1.00 | THRB (0.45) | THRBSPHK2SPHK1ESR1ADRA2A | |
| SCHEMBL5548831 | 0.95 | RELA (0.50) | THRBSPHK2SPHK1ESR1ADRA2A | |
| SCHEMBL5551483 | 0.94 | RELA (0.49) | THRBSPHK2SPHK1ESR1ADRA2A | |
| SCHEMBL15465910 | 0.94 | RELA (0.49) | THRBSPHK2SPHK1ESR1ADRA2A | |
| SCHEMBL29266162 | 0.92 | ESR1 (0.43) | THRBESR1ADRA2AADORA3TACR2 | |
| SCHEMBL29266159 | 0.92 | ESR1 (0.43) | THRBESR1ADRA2AADORA3TACR2 | |
| SCHEMBL30969697 | 0.88 | SIGMAR1 (0.45) | ALDH1A1RELA | |
| SCHEMBL29266161 | 0.88 | SIGMAR1 (0.45) | ALDH1A1RELA | |
| SCHEMBL17879401 | 0.88 | CYP3A4 (0.44) | THRBSPHK2SPHK1ESR1ADRA2A | |
| SCHEMBL30969698 | 0.88 | SIGMAR1 (0.45) | ALDH1A1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435418-B1 | FUSED THIOPHENES, ARTICLES AND METHODS THEREOF | CORNING INC (US) | 2019-06-26 | — | — | EP | disclosed |
| US-8658059-B2 | Liquid crystal composite material and liquid crystal electro-optical display device | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2014-02-25 | — | — | US | disclosed |
| US-20120162593-A1 | LIQUID CRYSTAL COMPOSITE MATERIAL AND LIQUID CRYSTAL ELECTRO-OPTICAL DISPLAY DEVICE | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2012-06-28 | — | — | US | disclosed |
| US-20080142793-A1 | Organic Semiconductors | UNITED STATES AIR FORCE | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080142793-A1 | Organic Semiconductors | ACE, ACE2, TTN | THRB 2973/4885SPHK2 2496/4885SPHK1 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.