Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.54 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136730 | 0.95 | PLOD2 (0.55) | PLOD2NPC1PLK1PLOD3PLOD1 | |
| SCHEMBL12856295 | 0.88 | MMP1 (0.57) | PLOD2PLOD3PLOD1ALDH1A1L3MBTL1 | |
| SCHEMBL1115952 | 0.86 | GAA (0.52) | PLOD2NPC1PLOD3PLOD1ALDH1A1 | |
| SCHEMBL7627400 | 0.84 | NPC1 (0.72) | NPC1PLK1ALDH1A1PARP10RAB9A | |
| SCHEMBL11138996 | 0.84 | RARB (0.57) | PLOD2L3MBTL1PLA2G4B | |
| SCHEMBL11139462 | 0.84 | L3MBTL1 (0.56) | PLOD2PLK1PLOD3PLOD1ALDH1A1 | |
| SCHEMBL709889 | 0.83 | PLOD2 (0.64) | PLOD2NPC1PLOD3PLOD1ALDH1A1 | |
| SCHEMBL11139961 | 0.82 | RARB (0.60) | PLOD2L3MBTL1PLA2G4B | |
| SCHEMBL1180670 | 0.81 | PLOD2 (0.57) | PLOD2PLOD3PLOD1MAPTL3MBTL1 | |
| SCHEMBL3247389 | 0.81 | PLOD2 (0.60) | PLOD2PLOD3PLOD1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377289-A4 | HETEROCYCLIC COMPOUNDS FOR THERAPEUTIC USE | JB CHEMICALS & PHARMACEUTICALS (IN) | 2008-09-10 | — | — | EP | disclosed |
| EP-1377289-A2 | HETEROCYCLIC COMPOUNDS FOR THERAPEUTIC USE | J.B. Chemicals & Pharmaceuticals Ltd. (IN) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002074235-A2 | HETEROCYCLIC COMPOUNDS FOR THERAPEUTIC USE | J.B. CHEMICALS & PHARMACEUTICALS LTD (IN) | 2002-09-26 | — | — | WO | disclosed |
| US-6403629-B2 | 1-(P-(METHYLSULFONAMIDO)PHENYL)-3-TRIFLUOROMETHYL-5-PHENYLPYRA ZOLONE AND DERIVATIVES; ANTIINFLAMMATORY AGENTS | J.B. CHEMICAL AND PHARMACEUTICALS LIMITED (IN) | 2002-06-11 | — | — | US | disclosed |
| US-20010047023-A1 | New Heterocyclic compounds for therapeutic use | J.B. CHEMICALS & PHARMACEUTICALS LIMITED | 2001-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047023-A1 | New Heterocyclic compounds for therapeutic use | AADAC, NAT1, FPR1 | PLOD2 2358/4885NPC1 1438/4885PLK1 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.