⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556522 | 0.76 | HCAR2 (0.31) | — | |
| SCHEMBL10421646 | 0.74 | CHRNA7 (0.52) | — | |
| SCHEMBL3408218 | 0.73 | LOXL2 (0.50) | — | |
| SCHEMBL10651306 | 0.72 | — | — | |
| SCHEMBL9285426 | 0.71 | MAOB (0.48) | — | |
| SCHEMBL887237 | 0.70 | — | — | |
| SCHEMBL8040576 | 0.70 | — | — | |
| SCHEMBL7547279 | 0.69 | ALDH1A1 (0.46) | — | |
| SCHEMBL1274793 | 0.66 | — | — | |
| SCHEMBL1274791 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128374-A1 | INSULIN-SIRNA CONJUGATES | SANOFI (FR) | 2011-10-20 | — | — | WO | claimed |
| US-11707483-B2 | Micellic assemblies | UNIVERSITY OF WASHINGTON (US) | 2023-07-25 | — | — | US | disclosed |
| US-20200147121-A1 | MICELLIC ASSEMBLIES | UNIVERSITY OF WASHINGTON (US) | 2020-05-14 | — | — | US | disclosed |
| US-10420790-B2 | Micellic assemblies | UNIVERSITY OF WASHINGTON (US) | 2019-09-24 | — | — | US | disclosed |
| US-10195284-B2 | Compositions and methods for controlled localized delivery of bone forming therapeutic agents | UNIVERSITY OF ROCHESTER (US) | 2019-02-05 | — | — | US | disclosed |
| US-10066043-B2 | ω-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization | UNIVERSITY OF WASHINGTON (US) | 2018-09-04 | — | — | US | disclosed |
| US-9949950-B2 | Compositions and methods for controlled localized delivery of bone forming therapeutic agents | UNIVERSITY OF ROCHESTER (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170239360-A1 | MICELLIC ASSEMBLIES | UNIVERSITY OF WASHINGTON (US) | 2017-08-24 | — | — | US | disclosed |
| US-9662403-B2 | Micellic assemblies | UNIVERSITY OF WASHINGTON (US) | 2017-05-30 | — | — | US | disclosed |
| US-20170145141-A1 | OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION | UNIVERSITY OF WASHINGTON (US) | 2017-05-25 | — | — | US | disclosed |
| CN-101437943-A | Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease | BALTIC TECHNOLOGY DEV LTD (EE) | 2009-05-20 | — | — | CN | disclosed |
| EP-2013344-A2 | ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE | Baltic Technology Development, Ltd. (EE) | 2009-01-14 | — | — | EP | disclosed |
| US-20070259830-A1 | Antisense Agents Combining Strongly Bound Base-Modified Oligonucleotide and Artificial Nuclease | BALTIC TECHNOLOGY DEVELOPMENT (EE) | 2007-11-08 | — | — | US | disclosed |
| WO-2007125173-A2 | ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE | BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) | 2007-11-08 | — | — | WO | disclosed |
| US-5596091-A | DNA AND RNA FOR GENE EXPRESSION FOR DIAGNOSIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-01-21 | — | — | US | disclosed |
| US-4933325-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE & CO. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4880829-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE AND COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4847241-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4822775-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0215297-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | disclosed |