Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587488 | 0.87 | NOD1 (0.42) | NOD1GLO1 | |
| SCHEMBL4588864 | 0.84 | MAPT (0.38) | ITGB3ITGA2BPPARG | |
| SCHEMBL4588856 | 0.84 | MAPT (0.38) | ITGB3ITGA2BPPARG | |
| SCHEMBL4587674 | 0.83 | LTA4H (0.36) | LTA4HNOD1PPARG | |
| SCHEMBL4587718 | 0.82 | CA12 (0.38) | — | |
| SCHEMBL4587704 | 0.82 | CA12 (0.38) | — | |
| SCHEMBL4589071 | 0.82 | NOD1 (0.35) | LTA4HNOD1GLO1 | |
| SCHEMBL4589192 | 0.81 | TMEM97 (0.39) | LTA4H | |
| SCHEMBL4588474 | 0.81 | FOLH1 (0.37) | NOD1GLO1 | |
| SCHEMBL4586937 | 0.81 | NOD1 (0.36) | NOD1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | NITROMED, INC. (US) | 2008-11-20 | — | — | US | claimed |
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | NITROMED, INC. (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | PC, PDK1, NOS3 | LTA4H 1903/4885NOD1 767/4885ITGB3 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.