Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458885 | 0.82 | LMNA (0.40) | L3MBTL1NR1H2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3627117 | 0.77 | L3MBTL1 (0.35) | BTKL3MBTL1NR1H2NR1H3KDM4E | |
| SCHEMBL4637026 | 0.76 | NR1H2 (0.40) | L3MBTL1NR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL1819124 | 0.75 | HPGD (0.39) | NR1H2NR1H3ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL455592 | 0.75 | AKT2 (0.42) | BTKAKT2L3MBTL1CHEK1NR1H2 | |
| SCHEMBL2766385 | 0.72 | BTK (0.41) | BTKAKT2L3MBTL1CHEK1NR1H2 | |
| SCHEMBL577704 | 0.67 | L3MBTL1 (0.45) | BTKAKT2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23674812 | 0.63 | NR1H2 (0.42) | NR1H2NR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL16863686 | 0.63 | PTGS1 (0.42) | L3MBTL1KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL457221 | 0.63 | SMN1; SMN2 (0.42) | L3MBTL1NR1H2NR1H3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |