Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841794 | 0.85 | SIRT2 (0.54) | KDM4ERAF1PKMYT1SIRT2SIRT1 | |
| SCHEMBL29954688 | 0.79 | KDM4E (0.59) | KDM4EPOLBRAF1GAAATM | |
| SCHEMBL6754398 | 0.79 | MKNK1 (0.67) | SIRT2SIRT1SIRT3F7F3 | |
| SCHEMBL186161 | 0.79 | KDM4E (0.59) | KDM4EPOLBRAF1GAAATM | |
| SCHEMBL5228608 | 0.77 | KDM4E (0.50) | KDM4EPOLBGAAATMAPLNR | |
| SCHEMBL29730943 | 0.77 | CA5A (0.56) | KDM4EPOLBGAAATMMKNK1 | |
| Hydrochloric Acid SCHEMBL5227513 | 0.77 | KDM4E (0.57) | KDM4EPOLBRAF1GAAATM | |
| SCHEMBL2141359 | 0.77 | CA5A (0.56) | KDM4EPOLBGAAATMMKNK1 | |
| SCHEMBL520949 | 0.77 | KDM4E (0.69) | KDM4ERAF1PKMYT1SIRT2SIRT1 | |
| SCHEMBL2645556 | 0.77 | SIRT2 (0.47) | KDM4ERAF1PKMYT1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969940-A | 3-hydroxypyridone-5-amide compound and medical application thereof | 浙江大学 | 2023-10-31 | — | — | CN | claimed |
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | claimed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | claimed |
| US-20250262205-A1 | DUAL MAGL AND FAAH INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2025-08-21 | — | — | US | disclosed |
| US-12318383-B2 | Dual MAGL and FAAH inhibitors | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2025-06-03 | — | — | US | disclosed |
| CN-117736178-B | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4424683-A2 | DUAL MAGL AND FAAH INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| EP-3595665-B1 | DUAL MAGL AND FAAH INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2024-08-28 | — | — | EP | disclosed |
| CN-118271288-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117736178-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4335848-A2 | DUAL MAGL AND FAAH INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-1997009979-A9 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | — | 1997-06-05 | — | — | WO | disclosed |
| EP-0634400-B1 | PYRIDINECARBOXIMIDAMIDE COMPOUND AND USE THEREOF | KIRIN BREWERY (JP) | 1997-04-02 | — | — | EP | disclosed |
| WO-1997009979-A1 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | FLORIDA STATE UNIVERSITY (US) | 1997-03-20 | — | — | WO | disclosed |
| US-5508293-A | TREATING HYPERTENSION, ANGINA PECTORIS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0634400-A1 | PYRIDINECARBOXIMIDAMIDE COMPOUND AND USE THEREOF | KIRIN BEER KABUSHIKI KAISHA (JP) | 1995-01-18 | — | — | EP | disclosed |
| CN-1077949-A | Pyridine carboxy imido acid amide compound and application thereof | KIRIN BREWERY (JP) | 1993-11-03 | — | — | CN | disclosed |
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250262205-A1 | DUAL MAGL AND FAAH INHIBITORS | FAAH, FAAH2, MAG | KDM4E 3236/4885POLB 3776/4885RAF1 478/4885 |
| US-12318383-B2 | Dual MAGL and FAAH inhibitors | FAAH, FAAH2, MAG | KDM4E 3236/4885POLB 3776/4885RAF1 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.