Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379813 | 0.81 | CYP2D6 (0.59) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9347229 | 0.80 | CYP2D6 (0.54) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL8536110 | 0.80 | CYP2D6 (0.36) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL7904051 | 0.80 | CYP2D6 (0.36) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL21002165 | 0.76 | CYP2D6 (0.67) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL51058 | 0.76 | CYP2D6 (0.67) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL7482872 | 0.76 | ALDH1A1 (0.40) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9435626 | 0.75 | LMNA (0.41) | CYP2D6ALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL5636034 | 0.74 | KLF10 (0.78) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL1229448 | 0.74 | ESR1 (0.71) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946456-B2 | Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol and (R)-feso-deacyl | CHEMI S.P.A. (IT) | 2015-02-03 | — | — | US | disclosed |
| EP-2580203-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | CHEMI SPA (IT) | 2014-08-13 | — | — | EP | disclosed |
| EP-2580203-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | Chemi SPA (IT) | 2013-04-17 | — | — | EP | disclosed |
| US-20130079532-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | CHEMI S.P.A. (IT) | 2013-03-28 | — | — | US | disclosed |
| WO-2011154854-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | CHEMI SPA (IT) | 2011-12-15 | — | — | WO | disclosed |
| US-20080166362-A1 | New effector conjugates, process for their production and their pharmaceutical use | BERGER MARKUS | 2008-07-10 | — | — | US | disclosed |
| US-7335775-B2 | Effector conjugates, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2008-02-26 | — | — | US | disclosed |
| US-20070088060-A1 | New effector conjugates, process for their production and their pharmaceutical use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-04-19 | — | — | US | disclosed |
| US-7129254-B2 | Effector conjugates, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-10-31 | — | — | US | disclosed |
| EP-1524979-A2 | NEW EFFECTOR CONJUGATES, PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | Schering AG (DE) | 2005-04-27 | — | — | EP | disclosed |
| US-20050026971-A1 | New effector conjugates, process for their production and their pharmaceutical use | SCHERING AG (DE) | 2005-02-03 | — | — | US | disclosed |
| WO-2004012735-A2 | NEW EFFECTOR CONJUGATES, PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 2004-02-12 | — | — | WO | disclosed |
| US-5231113-A | Skin disorders, immunology or wound healing agents | ALLERGAN, INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0337689-B1 | TETRALIN ESTERS OF PHENOLS OR BENZOIC ACIDS HAVING RETINOID LIKE ACTIVITY | ALLERGAN, INC (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5130335-A | Treatment of skin disorders | ALLERGAN, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0337689-A1 | Tetralin esters of phenols or benzoic acids having retinoid like activity | ALLERGAN, INC (US) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166362-A1 | New effector conjugates, process for their production and their pharmaceutical use | EPOR, TIE1, TEK | CYP2D6 3306/4885ALDH1A1 1845/4885HPGD 630/4885 |
| US-20050026971-A1 | New effector conjugates, process for their production and their pharmaceutical use | EPOR, TIE1, TEK | CYP2D6 3306/4885ALDH1A1 1845/4885HPGD 630/4885 |
| US-20070088060-A1 | New effector conjugates, process for their production and their pharmaceutical use | EPOR, TIE1, TEK | CYP2D6 3306/4885ALDH1A1 1845/4885HPGD 630/4885 |
| US-20130079532-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | FES, MAOB, BPHL | CYP2D6 31/4885ALDH1A1 1823/4885HPGD 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.