Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.48 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6751733 | 0.98 | PARP1 (0.55) | PARP1CA12CA2CA9CA1 | |
| SCHEMBL4190867 | 0.84 | PARP1 (0.61) | PARP1CA12CA2CA9CA1 | |
| SCHEMBL8084159 | 0.84 | CA12 (0.57) | PARP1CA12CA2CA9CA1 | |
| Hydrochloric Acid SCHEMBL2569130 | 0.82 | CA12 (0.55) | PARP1CA12CA2CA9CA1 | |
| SCHEMBL2989006 | 0.82 | CA12 (0.55) | PARP1CA12CA2CA9CA1 | |
| SCHEMBL9040297 | 0.81 | PARP1 (0.60) | PARP1MEN1KMT2A | |
| SCHEMBL9041395 | 0.81 | PBRM1 (0.53) | CA12CA2CA9CA1KDM4E | |
| SCHEMBL25170496 | 0.79 | CA12 (0.52) | PARP1CA12CA2CA9CA1 | |
| SCHEMBL3851904 | 0.79 | SLC6A2 (0.59) | PARP1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9040971 | 0.79 | PARP1 (0.58) | PARP1ALDH1A1GAACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911660-B1 | PROCESS FOR PREPARATION OF 2-AMINO-5-HYDROXY PROPIOPHENONE | LAURUS LABS LTD (IN) | 2023-05-10 | — | — | EP | claimed |
| CN-115387113-A | Far infrared deodorization fabric and preparation method thereof | 郑喜才 | 2022-11-25 | — | — | CN | claimed |
| EP-1910269-B1 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | AVRA LAB PVT LTD (IN) | 2013-09-18 | — | — | EP | claimed |
| US-7608740-B2 | Method of synthesizing key intermediates for the production of camptothecin derivatives | Avra Laboratories Pvt. Ltd (IN) | 2009-10-27 | — | — | US | claimed |
| US-20080221358-A1 | Method of Synthesizing Key Intermediates for the Production of Camptothecin Derivatives | AVRA LABORATORIES PVT. LTD. (IN) | 2008-09-11 | — | — | US | claimed |
| EP-1910269-A2 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | Avra Laboratories PVT. Ltd. (IN) | 2008-04-16 | — | — | EP | claimed |
| WO-2007015259-A2 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | AVRA LABORATORIES PVT. LTD. (IN) | 2007-02-08 | — | — | WO | claimed |
| CN-115387113-A | Far infrared deodorization fabric and preparation method thereof | 郑喜才 | 2022-11-25 | — | — | CN | disclosed |
| CN-115387113-A | Far infrared deodorization fabric and preparation method thereof | 郑喜才 | 2022-11-25 | — | — | CN | disclosed |
| EP-3911660-A1 | PROCESS FOR PREPARATION OF 2-AMINO-5-HYDROXY PROPIOPHENONE | Laurus Labs Limited (IN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020148641-A1 | PROCESS FOR PREPARATION OF 2-AMINO-5-HYDROXY PROPIOPHENONE | LAURUS LABS LIMITED (IN) | 2020-07-23 | — | — | WO | disclosed |
| EP-1378505-B1 | METHOD OF SYNTHESIZING CAMPTOTHECIN-RELATING COMPOUNDS | YAKULT HONSHA KK (JP) | 2014-11-05 | — | — | EP | disclosed |
| EP-1910269-B1 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | AVRA LAB PVT LTD (IN) | 2013-09-18 | — | — | EP | disclosed |
| US-20040048832-A1 | Compounds useful in preparing camptothecin derivatives | PHARMACIA CORPORATION | 2004-03-11 | — | — | US | disclosed |
| EP-1378505-A1 | METHOD OF SYNTHESIZING CAMPTOTHECIN-RELATING COMPOUNDS | Kabushiki Kaisha Yakult Honsha (JP) | 2004-01-07 | — | — | EP | disclosed |
| WO-2003089413-A1 | PHARMACIA CORPORATION | PHARMACIA CORPORATION (US) | 2003-10-30 | — | — | WO | disclosed |
| CN-1031941-C | Process for preparing fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-06-05 | — | — | CN | disclosed |
| EP-0471358-B1 | Fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-05-08 | — | — | EP | disclosed |
| CN-1060095-A | Fluoroethylcamptothederivatives derivatives | KYORIN SEIYAKU KK (JP) | 1992-04-08 | — | — | CN | disclosed |
| EP-0471358-A1 | Fluoroethylcamptothecin derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221358-A1 | Method of Synthesizing Key Intermediates for the Production of Camptothecin Derivatives | DHPS, TOP2A, HCCS | PARP1 308/4885CA12 3479/4885CA2 3987/4885 |
| US-20040048832-A1 | Compounds useful in preparing camptothecin derivatives | TOP2A, TOP2B, TOP1 | PARP1 69/4885CA12 4032/4885CA2 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.