SCHEMBL2989006

SCHEMBL2989006

CC(O)C(=O)c1cccc(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
CA1 P00915 1/20 0.55
CA6 P23280 1/20 0.55
PARP1 P09874 1/20 0.53
KDM4E B2RXH2 5/20 0.50
EGLN2 Q96KS0 1/20 0.50
ALDH1A1 P00352 2/20 0.48
FASN P49327 1/20 0.47
GAA P10253 2/20 0.46
MAPT P10636 1/20 0.46
CLK1 P49759 2/20 0.46
DYRK1A Q13627 2/20 0.46
DYRK1B Q9Y463 2/20 0.46
ADRB1 P08588 2/20 0.43
MIF P14174 1/20 0.43
HTR2A P28223 1/20 0.43
ADRA1A P35348 1/20 0.43
HTR2B P41595 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084159 0.86 CA12 (0.57) CA12CA2CA9CA1CA6
SCHEMBL25170496 0.85 CA12 (0.52) CA12CA2CA9CA1CA6
Hydrochloric Acid SCHEMBL2569130 0.84 CA12 (0.55) CA12CA2CA9CA1CA6
SCHEMBL459041 0.82 PARP1 (0.57) CA12CA2CA9CA1CA6
Hydrochloric Acid SCHEMBL6751733 0.81 PARP1 (0.55) CA12CA2CA9CA1CA6
SCHEMBL1305879 0.80 SLC6A2 (0.57) PARP1ADRB1ADRB2ADRB3MEN1
SCHEMBL28583896 0.80 CA12 (0.55) CA12CA2CA9CA1CA6
SCHEMBL3850377 0.80 CA12 (0.61) CA12CA2CA9CA1CA6
SCHEMBL8875628 0.80 CA12 (0.50) CA12CA2CA9CA1CA6
SCHEMBL15007483 0.80 SLC6A2 (0.57) PARP1ADRB1ADRB2ADRB3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
EP-4702104-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUND Merck Patent GmbH (DE) 2026-03-04 EP disclosed
EP-4514919-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS Merck Patent GmbH (DE) 2025-03-05 EP disclosed
WO-2024223484-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUND MERCK PATENT GMBH (DE) 2024-10-31 WO disclosed
WO-2023208801-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-11-02 WO disclosed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-7834210-B2 Hair loss prevention by natural amino acid and peptide complexes BIODERM RESEARCH (US) 2010-11-16 US disclosed
EP-0653455-B1 FILM FOR METAL LAMINATION TEIJIN LTD (JP) 1997-10-01 EP disclosed
EP-0653455-A1 FILM FOR METAL LAMINATION TEIJIN LIMITED (JP) 1995-05-17 EP disclosed
US-4788215-A TREATMENT OF HYPERTHYROIDISM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-11-29 US disclosed
US-4713465-A Flavanone intermediates for halogenohydroxyflavones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-12-15 US disclosed
EP-0032063-B1 NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1984-03-14 EP disclosed
US-4351950-A Anti-arteriosclerotic agents WARNER-LAMBERT COMPANY (US) 1982-09-28 US disclosed
EP-0032063-A2 Novel substituted arylene compounds and processes for their production WARNER-LAMBERT COMPANY (US) 1981-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 CA12 2732/4885CA2 1234/4885CA9 1035/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA CA12 4776/4885CA2 4627/4885CA9 4380/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA CA12 4408/4885CA2 1976/4885CA9 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.