Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539903 | 0.88 | MAPT (0.45) | CTBP2ALDH1A1FAAHMGLLL3MBTL1 | |
| SCHEMBL11537202 | 0.88 | LTA4H (0.50) | CTBP2ALDH1A1FAAHMGLLMAPT | |
| SCHEMBL11084515 | 0.80 | CA2 (0.41) | CTBP2ALDH1A1FAAHMGLLMAPT | |
| SCHEMBL10610797 | 0.80 | ALDH1A1 (0.47) | CTBP2ALDH1A1FAAHMGLLL3MBTL1 | |
| SCHEMBL1999167 | 0.78 | IDO1 (0.52) | CTBP2ALDH1A1FAAHMGLLL3MBTL1 | |
| SCHEMBL11081484 | 0.77 | TSHR (0.50) | TDP1LMNA | |
| SCHEMBL10524113 | 0.77 | CA2 (0.58) | CTBP2ALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL28210144 | 0.76 | IDO1 (0.50) | IDO1MEN1KMT2ATAAR1 | |
| SCHEMBL4066362 | 0.76 | L3MBTL1 (0.52) | CTBP2ALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL1096270 | 0.76 | CES1 (0.55) | CTBP2ALDH1A1L3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496175-A | TRADD inhibitor derivative and preparation method and application thereof | 安徽医科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118496175-A | TRADD inhibitor derivative and preparation method and application thereof | 安徽医科大学 | 2024-08-16 | — | — | CN | disclosed |
| US-11932653-B2 | Lycorine derivative, and pharmaceutical composition and use thereof | SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD (CN) | 2024-03-19 | — | — | US | disclosed |
| US-20210206777-A1 | LYCORINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD (CN) | 2021-07-08 | — | — | US | disclosed |
| CN-107722049-B | Preparation and application of novel ionic binuclear Schiff base titanium complex | 山西医科大学 | 2020-06-30 | — | — | CN | disclosed |
| WO-2020019357-A1 | LYCORINE DERIVATIVES, PHARMACEUTICAL COMPOSITE THEREOF AND USAGE THEREFOR | 山东达因海洋生物制药股份有限公司 | 2020-01-30 | — | — | WO | disclosed |
| US-7442485-B2 | Lithographic process involving on press development | FUJIFILM CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
| EP-1484177-B1 | Lithographic process involving on press development | FUJIFILM CORP (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-20050016402-A1 | Lithographic process involving on press development | FUJI PHOTO FILM CO., LTD. | 2005-01-27 | — | — | US | disclosed |
| EP-1484177-A2 | Lithographic process involving on press development | FUJI PHOTO FILM CO., LTD. (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-0207690-B1 | N-SUBSTITUTED GLUTAMIC ACID DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF | SUNTORY LIMITED (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0146297-B1 | SUBSTITUTED TRANS-1,2-DIAMINOCYCLOHEXYL AMIDE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4701210-A | HERBICIDES | SUNTORY LIMITED (JP) | 1987-10-20 | — | — | US | disclosed |
| US-4677122-A | ANALGESICS, DIURETICS | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0207690-A1 | N-Substituted glutamic acid derivative and process for production and use thereof | SUNTORY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |
| US-4598087-A | DIURETICS; ANALGESICS, PSYCHOTHERAPEUTICS | WARNER-LAMBERT COMPANY (US) | 1986-07-01 | — | — | US | disclosed |
| EP-0146297-A1 | Substituted trans-1,2-diaminocyclohexyl amide compounds | WARNER-LAMBERT COMPANY (US) | 1985-06-26 | — | — | EP | disclosed |
| EP-0027895-A1 | 1-(2-(Alkyl and arylsulfonyl)-2-propenyl and propyl) substituted piperidines and pharmaceutical and antimicrobial compositions comprising the same | MERCK & CO. INC. (US) | 1981-05-06 | — | — | EP | disclosed |
| US-4244963-A | 1-[2-(Alkyl and arylsulfonyl)-2-propenyl and propyl] substituted piperidines useful as antimicrobial and antiinflammatory agents | MERCK & CO., INC. (US) | 1981-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932653-B2 | Lycorine derivative, and pharmaceutical composition and use thereof | LCT, LARP7, LASP1 | CTBP2 4530/4885ALDH1A1 2939/4885FAAH 3663/4885 |
| US-20210206777-A1 | LYCORINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | LARP7, LARP1, LASP1 | CTBP2 4476/4885ALDH1A1 2613/4885FAAH 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.