Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883956 | 0.78 | LMNA (0.42) | LMNAFAAHCES2APEX1CES1 | |
| SCHEMBL5842389 | 0.78 | ALDH1A1 (0.34) | LMNA | |
| SCHEMBL9883954 | 0.78 | APEX1 (0.52) | LMNAAPEX1 | |
| SCHEMBL8774964 | 0.77 | APEX1 (0.36) | APEX1 | |
| SCHEMBL9835512 | 0.75 | APP (0.46) | LMNAAPEX1 | |
| SCHEMBL5842384 | 0.73 | ARG1 (0.31) | — | |
| SCHEMBL25071530 | 0.73 | ALDH1A1 (0.58) | LMNAFAAHCES2APEX1CES1 | |
| SCHEMBL777041 | 0.73 | CA2 (0.48) | LMNAFAAHCES2CES1CA2 | |
| SCHEMBL7769895 | 0.71 | ALDH1A1 (0.38) | LMNA | |
| SCHEMBL2610344 | 0.71 | AKR1B1 (0.54) | LMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902100-A2 | REACTIVE DYES, A PROCESS FOR THEIR PREPARATION AND THEIR USE | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2008-03-26 | — | — | EP | claimed |
| WO-2007006653-A2 | REACTIVE DYES, A PROCESS FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (DE) | 2007-01-18 | — | — | WO | claimed |
| EP-1902100-A2 | REACTIVE DYES, A PROCESS FOR THEIR PREPARATION AND THEIR USE | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007006653-A2 | REACTIVE DYES, A PROCESS FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (DE) | 2007-01-18 | — | — | WO | disclosed |