Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 6/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141769 | 0.76 | FDPS (0.45) | ALDH1A1TSHRMEN1GAAPKM | |
| SCHEMBL11550826 | 0.75 | FDPS (0.44) | ALDH1A1TSHRMEN1GAAPKM | |
| SCHEMBL4120852 | 0.75 | FDPS (0.43) | ALDH1A1MEN1PKMKMT2AFDPS | |
| SCHEMBL9845391 | 0.70 | CYP2C19 (0.44) | ALDH1A1TSHRMEN1GAAPKM | |
| SCHEMBL8149023 | 0.70 | FDPS (0.39) | ALDH1A1TSHRMEN1GAAPKM | |
| SCHEMBL8324373 | 0.69 | FFAR1 (0.41) | ALDH1A1TSHRMEN1GAAPKM | |
| Diphenylsulfane SCHEMBL9028896 | 0.69 | HPGD (0.54) | ALDH1A1MEN1KMT2AKCNH2CFTR | |
| Diphenylsulfane SCHEMBL28287035 | 0.68 | HPGD (0.52) | ALDH1A1TSHRPTPN1CFTRHPGD | |
| SCHEMBL17766185 | 0.68 | FFAR1 (0.39) | ALDH1A1TSHRMEN1GAAPKM | |
| SCHEMBL7324259 | 0.68 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799638-B1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA HOLDING INC (CH) | 2008-07-30 | — | — | EP | claimed |
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5166019-A | Light sensitive elements | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |