Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 4/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592580 | 0.75 | ALDH1A1 (0.41) | FDPSTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL10630052 | 0.72 | CYP2C19 (0.43) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL3889472 | 0.71 | FDPS (0.36) | FDPSGGPS1 | |
| SCHEMBL9069763 | 0.70 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2D6PRMT1SMN1; SMN2 | |
| SCHEMBL12879664 | 0.70 | CYP2D6 (0.68) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL7263779 | 0.69 | FDPS (0.58) | FDPSCYP1A2SMN1; SMN2TSHRCETP | |
| SCHEMBL7605699 | 0.68 | FDPS (0.61) | FDPSCYP1A2SMN1; SMN2TSHRKMT2A | |
| SCHEMBL9231165 | 0.68 | ACHE (0.42) | FDPSALPLALPIALPGHTT | |
| SCHEMBL9000117 | 0.68 | FDPS (0.31) | FDPS | |
| SCHEMBL6681928 | 0.67 | ALPL (0.47) | FDPSALPLALPIALPGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169849-A | 11-DESOXY-15-THIAPROSTAGLANDINS | PFIZER INC. (US) | 1979-10-02 | — | — | US | disclosed |
| US-4148804-A | ANTIULCER AGENTS, SELECTIVITY | PFIZER INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4092349-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1978-05-30 | — | — | US | disclosed |