Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593009 | 0.82 | HTR2C (0.57) | HTR2CTSHRMTNR1APKMHTR2A | |
| SCHEMBL4593095 | 0.77 | HTR2A (0.40) | HTR2CTSHRMTNR1APKMHTR2A | |
| SCHEMBL19799069 | 0.75 | PKM (0.39) | TP53TSHRSMN1; SMN2MTNR1APKM | |
| SCHEMBL616083 | 0.74 | ALDH1A1 (0.69) | HTR2CALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL989652 | 0.74 | HTR2A (0.58) | HTR2CMTNR1AHTR2A | |
| SCHEMBL28070559 | 0.74 | HTR2A (0.58) | HTR2CMTNR1AHTR2A | |
| SCHEMBL30449882 | 0.74 | HTR2A (0.58) | HTR2CMTNR1AHTR2A | |
| SCHEMBL13523863 | 0.72 | MAOB (0.49) | MTNR1A | |
| SCHEMBL5179342 | 0.71 | PDE10A (0.50) | CYP3A4HTR2APDE10A | |
| SCHEMBL1448749 | 0.71 | PTGS1 (0.53) | TP53CYP3A4TSHRSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900723-A1 | New naphthalene derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2008-03-19 | — | — | EP | disclosed |
| US-20080004348-A1 | Naphthalene compounds | LES LABORATOIRES SERVIER (FR) | 2008-01-03 | — | — | US | disclosed |
| WO-2008000969-A1 | NOVEL NAPHTHALENIC DERIVATIVES, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004348-A1 | Naphthalene compounds | MTNR1A, MTNR1B, CNR1 | HTR2C 53/4885ALDH1A1 658/4885TP53 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.