Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286240 | 0.69 | ACHE (0.40) | ACHETDP1MAOBMAOALMNA | |
| SCHEMBL4594159 | 0.68 | ACHE (0.35) | ACHETDP1MAOBMAOALMNA | |
| SCHEMBL29278372 | 0.67 | ACHE (0.38) | ACHETDP1MAOBMAOALMNA | |
| P-Xylene SCHEMBL17784277 | 0.65 | ACHE (0.67) | ACHETDP1LMNA | |
| SCHEMBL16877179 | 0.64 | ACHE (0.35) | ACHETDP1MAOBMAOALMNA | |
| SCHEMBL19033437 | 0.62 | ACHE (0.44) | ACHETDP1MAOBMAOA | |
| P-Xylene SCHEMBL2589553 | 0.62 | ACHE (0.61) | ACHETDP1LMNAHPGD | |
| P-Xylene SCHEMBL11301004 | 0.62 | ACHE (0.61) | ACHETDP1MAOBMAOALMNA | |
| SCHEMBL13619662 | 0.61 | KIF11 (0.45) | ACHETDP1MAOBMAOALMNA | |
| SCHEMBL21183996 | 0.59 | ACHE (0.40) | ACHETDP1MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937257-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007037685-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-04-05 | — | — | WO | disclosed |