Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593190 | 0.78 | SLC6A3 (0.33) | MAOBMAOACYP19A1IDO1 | |
| SCHEMBL4593434 | 0.77 | TSHR (0.35) | MAOBMAOATSHR | |
| SCHEMBL4593654 | 0.75 | MAOA (0.40) | MAOBMAOAALDH1A1TSHRCYP19A1 | |
| SCHEMBL13619662 | 0.71 | KIF11 (0.45) | ACHETDP1MAOBMAOATSHR | |
| SCHEMBL5286240 | 0.70 | ACHE (0.40) | ACHETDP1MAOBMAOAALDH1A1 | |
| SCHEMBL16877179 | 0.70 | ACHE (0.35) | ACHETDP1MAOBMAOAALDH1A1 | |
| SCHEMBL29278372 | 0.68 | ACHE (0.38) | ACHETDP1MAOBMAOAALDH1A1 | |
| SCHEMBL4593516 | 0.68 | ACHE (0.33) | ACHETDP1MAOBMAOAHSP90AA1 | |
| SCHEMBL30810730 | 0.67 | KIF11 (0.53) | MAOBMAOANPC1 | |
| P-Xylene SCHEMBL15515891 | 0.66 | ACHE (0.67) | ACHETDP1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937257-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007037685-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-04-05 | — | — | WO | disclosed |