SCHEMBL4593996

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4594578	0.95	SMN1; SMN2 (0.39)	MMP2MMP9KDM4EALDH1A1TDP1
	SCHEMBL4594020	0.94	PAOX (0.38)	MMP2MMP9PAOXKDM4EALDH1A1
	SCHEMBL4593885	0.89	SMN1; SMN2 (0.39)	MMP2MMP9KDM4EALDH1A1TDP1
	SCHEMBL4594077	0.89	KDM4E (0.39)	MMP2MMP9KDM4EALDH1A1TDP1
	SCHEMBL4593556	0.88	PAOX (0.38)	PAOXKDM4EALDH1A1TDP1CYP2D6
	SCHEMBL4594912	0.86	ALDH1A1 (0.38)	KDM4EALDH1A1TDP1CYP2D6CYP2C19
	SCHEMBL4593088	0.83	SMN1; SMN2 (0.39)	PAOXKDM4EALDH1A1TDP1CYP2D6
	SCHEMBL4586997	0.77	KDM4E (0.40)	PAOXKDM4ECYP2D6CYP2C19KMT2A
	SCHEMBL4588394	0.76	APEX1 (0.36)	KDM4EALDH1A1TDP1MAPTSMN1; SMN2
	SCHEMBL14607630	0.76	GNAI3 (0.38)	MMP2MMP9ALDH1A1MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.