Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | DNM1L | O00429 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062975 | 0.82 | SLC6A3 (0.48) | SLC6A3GFERALDH1A1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7181165 | 0.81 | SLC6A3 (0.47) | SLC6A3GFERALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1118089 | 0.80 | SLC6A3 (0.40) | SLC6A3SMN1; SMN2KMT2AAOC3GPR119 | |
| SCHEMBL9065445 | 0.79 | DRD2 (0.43) | SLC6A3GFERALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9265855 | 0.79 | SLC6A3 (0.43) | SLC6A3GFERALDH1A1TDP1L3MBTL1 | |
| SCHEMBL12036245 | 0.79 | BAZ2A (0.43) | SLC6A3SMN1; SMN2KMT2AAOC3GPR119 | |
| Hydrochloric Acid SCHEMBL7184215 | 0.78 | SLC6A3 (0.42) | SLC6A3GFERALDH1A1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7174596 | 0.78 | DRD2 (0.42) | SLC6A3GFERALDH1A1TDP1L3MBTL1 | |
| SCHEMBL459218 | 0.74 | DNM1L (0.38) | SLC6A3AOC3GPR119DNM1L | |
| SCHEMBL27768211 | 0.74 | GPR119 (0.42) | SLC6A3ALDH1A1TDP1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |