Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973926 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL15154690 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL27338533 | 0.81 | CASP6 (0.54) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL11626358 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL5657418 | 0.78 | MAOA (0.49) | ALDH1A1TDP1MAPTL3MBTL1LMNA | |
| SCHEMBL28288279 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL18162301 | 0.78 | PIN1 (0.51) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL5941164 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HPRT1TDP1TSHRMAPT | |
| SCHEMBL29097580 | 0.76 | NPC1 (0.52) | ALDH1A1HPRT1MAPTL3MBTL1HPGD | |
| SCHEMBL20897727 | 0.76 | PDE10A (0.61) | ALDH1A1TDP1TSHRMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590558-A | Method for catalyzing selective nitration of 1-methoxynaphthalene by using zeolite molecular sieve | 蚌埠学院 | 2019-12-20 | — | — | CN | claimed |
| CN-110590558-A | Method for catalyzing selective nitration of 1-methoxynaphthalene by using zeolite molecular sieve | 蚌埠学院 | 2019-12-20 | — | — | CN | disclosed |
| US-10471139-B2 | Toll-like receptor agonists | THE UNIVERSITY OF KANSAS (US) | 2019-11-12 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |
| US-20080255232-A1 | Naphthyl Derivatives as Inhibitors of Beta-Amyloid Aggregation | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-10-16 | — | — | US | disclosed |
| US-20080255232-A1 | Naphthyl Derivatives as Inhibitors of Beta-Amyloid Aggregation | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-10-16 | — | — | US | disclosed |
| US-20080255232-A1 | Naphthyl Derivatives as Inhibitors of Beta-Amyloid Aggregation | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-10-16 | — | — | US | disclosed |
| EP-1937243-A2 | NAPHTHYL DERIVATIVES AS INHIBITORS OF BETA-AMYLOID AGGREGATION | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007045593-A2 | NAPHTHYL DERIVATIVES AS INHIBITORS OF BETA-AMYLOID AGGREGATION | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007045593-A2 | NAPHTHYL DERIVATIVES AS INHIBITORS OF BETA-AMYLOID AGGREGATION | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-04-26 | — | — | WO | disclosed |
| EP-0335274-B1 | Formation of nitrophenyl ethers from polyols and nitroanisoles | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | disclosed |
| US-4960950-A | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0335274-A2 | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | TLR1, TLR7, TLR8 | ALDH1A1 1952/4885HPRT1 2022/4885TDP1 366/4885 |
| US-10471139-B2 | Toll-like receptor agonists | TLR1, TLR7, TLR8 | ALDH1A1 1952/4885HPRT1 2022/4885TDP1 366/4885 |
| US-20080255232-A1 | Naphthyl Derivatives as Inhibitors of Beta-Amyloid Aggregation | APP, BACE1, SNCA | ALDH1A1 1775/4885HPRT1 1579/4885TDP1 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.