Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596675 | 0.85 | AQP1 (0.37) | AQP1TDP1L3MBTL1 | |
| SCHEMBL4596103 | 0.85 | AQP1 (0.43) | AQP1L3MBTL1 | |
| SCHEMBL4596492 | 0.83 | AQP1 (0.36) | AQP1 | |
| SCHEMBL4595082 | 0.81 | AQP1 (0.33) | AQP1 | |
| SCHEMBL4596399 | 0.79 | HTR1A (0.34) | AQP1TDP1L3MBTL1 | |
| SCHEMBL4595484 | 0.79 | AQP1 (0.51) | AQP1 | |
| SCHEMBL6047944 | 0.77 | P2RX7 (0.38) | TDP1L3MBTL1 | |
| SCHEMBL4596984 | 0.76 | AQP1 (0.45) | AQP1L3MBTL1 | |
| SCHEMBL4596741 | 0.76 | AQP1 (0.48) | AQP1 | |
| SCHEMBL4596735 | 0.74 | AQP1 (0.47) | AQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |