Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595082 | 0.93 | AQP1 (0.33) | AQP1SIRT2 | |
| SCHEMBL4596399 | 0.91 | HTR1A (0.34) | AQP1DRD2DRD4DRD3TDP1 | |
| SCHEMBL6047944 | 0.89 | P2RX7 (0.38) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL4595481 | 0.85 | AQP1 (0.43) | AQP1TDP1L3MBTL1 | |
| SCHEMBL4596725 | 0.83 | CHRM1 (0.33) | AQP1SIRT2 | |
| SCHEMBL4596775 | 0.83 | AQP1 (0.40) | AQP1L3MBTL1 | |
| SCHEMBL6047967 | 0.81 | MAPK1 (0.33) | DRD2TDP1L3MBTL1 | |
| SCHEMBL4596928 | 0.76 | PRKAB2 (0.35) | — | |
| SCHEMBL4596984 | 0.76 | AQP1 (0.45) | AQP1L3MBTL1SIRT2 | |
| SCHEMBL4596492 | 0.76 | AQP1 (0.36) | AQP1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | disclosed |