Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229500 | 0.91 | MTNR1A (0.42) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4226255 | 0.88 | GPR52 (0.46) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4226025 | 0.85 | GPR52 (0.41) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4225917 | 0.84 | GPR52 (0.42) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4226726 | 0.80 | ALDH1A1 (0.43) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4220081 | 0.78 | ABCB1 (0.38) | MTNR1ANPC1RAB9ASMN1; SMN2MTNR1B | |
| SCHEMBL4232344 | 0.77 | MTNR1A (0.41) | MTNR1AMTNR1BMAPK1TSHR | |
| SCHEMBL4595700 | 0.77 | MYC (0.36) | HPGDSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL4222303 | 0.74 | PRKAB2 (0.41) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4232343 | 0.74 | L3MBTL1 (0.39) | MTNR1AHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007030150-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | disclosed |