SCHEMBL4596010

SCHEMBL4596010

CCCCCC(O)OC(=O)c1cccc(C(=O)OC(=O)c2ccccc2C(=O)OC(=O)c2cccc(C(=O)OC(CCCCC)OC(=O)CCCCC(=O)O)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
PRSS1 P07477 2/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
FFAR1 O14842 1/20 0.35
PPARG P37231 2/20 0.35
PPARA Q07869 1/20 0.35
CTSK P43235 1/20 0.35
PTGER1 P34995 1/20 0.34
PTGER4 P35408 1/20 0.34
PTGER3 P43115 1/20 0.34
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5951005 0.84 LTB4R (0.45) ALDH1A1KMT2AFFAR4FFAR1PPARG
Adipic Acid SCHEMBL8967488 0.81 LTB4R (0.47) ALDH1A1KMT2AFFAR4FFAR1PTGER1
SCHEMBL11104926 0.78 LTB4R (0.43) ALDH1A1KMT2AFFAR4FFAR1PPARG
SCHEMBL3877617 0.76 PLA2G4B (0.45) ALDH1A1KMT2ACTSKTSHRTP53
SCHEMBL5378258 0.74 LTB4R (0.44) FFAR4FFAR1PPARGPPARAPTGER1
SCHEMBL5178745 0.73 ALDH1A1 (0.54) ALDH1A1PRSS1PRSS2PRSS3KDM4E
SCHEMBL15903015 0.73 ALDH1A1 (0.48) ALDH1A1PRSS1PRSS2PRSS3MEN1
SCHEMBL27650049 0.73 CTSK (0.54) ALDH1A1PRSS1PRSS2PRSS3MEN1
SCHEMBL10791097 0.73 CTSK (0.54) ALDH1A1PRSS1PRSS2PRSS3MEN1
SCHEMBL2007985 0.73 MEN1 (0.52) ALDH1A1PRSS1PRSS2PRSS3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1137727-B1 AQUEOUS COATING COMPOSITIONS DU PONT (US) 2008-01-09 EP disclosed