Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598029 | 0.88 | PIK3C3 (0.33) | SLC6A9OPRM1OPRL1ALDH1A1POLB | |
| SCHEMBL4596509 | 0.88 | CYP2C19 (0.34) | SLC6A9OPRM1SLC6A5CNR2SIGMAR1 | |
| SCHEMBL4597794 | 0.78 | HCRTR1 (0.31) | — | |
| SCHEMBL4597411 | 0.71 | — | — | |
| SCHEMBL4598373 | 0.70 | GNAI3 (0.32) | — | |
| SCHEMBL3815921 | 0.67 | HSD17B10 (0.51) | SLC6A9OPRM1SIGMAR1OPRL1HSD17B10 | |
| SCHEMBL4597510 | 0.60 | KDM4E (0.32) | SLC6A9OPRM1OPRL1ALDH1A1 | |
| SCHEMBL4596041 | 0.60 | KDM4E (0.32) | SLC6A9OPRM1OPRL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4561643 | 0.60 | HSD17B10 (0.43) | SLC6A9OPRM1OPRL1HSD17B10GRIN1 | |
| SCHEMBL27747187 | 0.60 | SLC6A9 (0.46) | SLC6A9OPRM1SLC6A5OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |