Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596509 | 0.88 | CYP2C19 (0.34) | PIK3C3ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4596047 | 0.88 | SLC6A9 (0.36) | ALDH1A1POLBSLC6A9OPRM1OPRL1 | |
| SCHEMBL4597794 | 0.79 | HCRTR1 (0.31) | — | |
| SCHEMBL4597761 | 0.69 | KCNJ1 (0.44) | ALDH1A1MAPTCYP2C19 | |
| SCHEMBL4597411 | 0.67 | — | — | |
| SCHEMBL4598373 | 0.66 | GNAI3 (0.32) | — | |
| SCHEMBL4598027 | 0.65 | CHRNA1 (0.32) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL3900550 | 0.62 | USP2 (0.38) | ALDH1A1SLC6A9OPRM1OPRL1HSD11B1 | |
| SCHEMBL3910153 | 0.59 | OPRM1 (0.40) | ALDH1A1MEN1KMT2ASLC6A9OPRM1 | |
| SCHEMBL3860581 | 0.58 | ALDH1A1 (0.43) | ALDH1A1POLBSLC6A9OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |