Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598029 | 0.79 | PIK3C3 (0.33) | — | |
| SCHEMBL4596047 | 0.78 | SLC6A9 (0.36) | — | |
| SCHEMBL4596509 | 0.77 | CYP2C19 (0.34) | CYP3A4HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL4597411 | 0.68 | — | — | |
| SCHEMBL4625414 | 0.67 | CHRM2 (0.34) | PLATHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL4597792 | 0.67 | CHRM2 (0.34) | PLATHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL10062771 | 0.59 | OPRM1 (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL10062768 | 0.59 | OPRM1 (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL2271940 | 0.58 | SIGMAR1 (0.44) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16433641 | 0.56 | ALDH1A1 (0.35) | SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |