Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31011353 | 1.00 | CASP6 (0.72) | CASP6TSHRLMNAGPR35HCAR3 | |
| SCHEMBL2797668 | 0.87 | TPMT (0.58) | CASP6TSHRLMNAHCAR3CA12 | |
| SCHEMBL2405926 | 0.86 | CASP6 (0.59) | CASP6TSHRLMNAGPR35HCAR3 | |
| SCHEMBL106249 | 0.85 | CASP6 (0.72) | CASP6TSHRLMNAGPR35HCAR3 | |
| SCHEMBL2636747 | 0.85 | CASP6 (0.72) | CASP6TSHRLMNAGPR35HCAR3 | |
| SCHEMBL504055 | 0.84 | CASP6 (1.00) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL29577830 | 0.84 | CASP6 (1.00) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL9339498 | 0.83 | GPR35 (0.56) | CASP6TSHRLMNAGPR35KDM4E | |
| SCHEMBL1898142 | 0.83 | CASP6 (0.70) | CASP6TSHRLMNAGPR35HCAR3 | |
| SCHEMBL4305881 | 0.83 | GPR35 (0.56) | CASP6TSHRGPR35POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 939 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166605-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-05-23 | — | — | US | claimed |
| CN-115722210-B | Recursive nanofiber-based detection material and preparation method and application thereof | 广西大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117003404-A | High ammonia nitrogen wastewater treatment reagent | 苏州森荣环保处置有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-112851646-B | Preparation method of tergolian prazan | 中国医学科学院药物研究所 | 2023-06-13 | — | — | CN | claimed |
| CN-115722210-A | Recursive nanofiber-based detection material and preparation method and application thereof | 广西大学 | 2023-03-03 | — | — | CN | claimed |
| CN-115073296-B | Method and device for rapidly detecting propylene glycol in food | 深圳市易瑞生物技术股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| EP-4059921-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | Chiesi Farmaceutici S.p.A. (IT) | 2022-09-21 | — | — | EP | claimed |
| CN-115073296-A | Method and device for rapidly detecting propylene glycol in food | 深圳市易瑞生物技术股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-112851646-A | Preparation method of Tegolrazan | 中国医学科学院药物研究所 | 2021-05-28 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-5830999-A | CARBOXYLIC LIGANDS, HEXAMERS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-11-03 | — | — | US | claimed |
| EP-0519971-B1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE | INST SOZIAL MED FORSCHUNG SA (CH) | 1997-01-15 | — | — | EP | claimed |
| EP-0539274-B1 | Method for the synthesis of aldehydes and of their derivatives | RHONE POULENC CHIMIE (FR) | 1996-04-10 | — | — | EP | claimed |
| EP-0519971-A1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE. | EEC PHARMA SA (FR) | 1992-12-30 | — | — | EP | claimed |
| EP-0291865-B1 | ELECTROCHEMICAL SYNTHESIS OF SUBSTITUTED AROMATIC AMINES IN BASIC MEDIA | THE DOW CHEMICAL COMPANY (US) | 1992-08-12 | — | — | EP | claimed |
| WO-1991013886-A1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE | EEC-PHARMA S.A. (FR) | 1991-09-19 | — | — | WO | claimed |
| WO-1988009398-A1 | ELECTROCHEMICAL SYNTHESIS OF SUBSTITUTED AMINES IN BASIC MEDIA | THE DOW CHEMICAL COMPANY (US) | 1988-12-01 | — | — | WO | claimed |
| EP-0291865-A2 | Electrochemical synthesis of substituted aromatic amines in basic media | THE DOW CHEMICAL COMPANY (US) | 1988-11-23 | — | — | EP | claimed |
| US-4764263-A | Electrochemical synthesis of substituted aromatic amines in basic media | THE DOW CHEMICAL COMPANY (US) | 1988-08-16 | — | — | US | claimed |
| US-4005145-A | ISOMERIZATION OF A,B-UNSATURATED OXO COMPOUNDS TO B,G-ISOMER | HOFFMANN-LA ROCHE INC. (US) | 1977-01-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | CASP6 3234/4885TSHR 1605/4885LMNA 4734/4885 |
| US-20240166605-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | PDE4A, PDE12, PDE4B | CASP6 2338/4885TSHR 4158/4885LMNA 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.