SCHEMBL459657

SCHEMBL459657

O=C(c1ccccc1Oc1ccccc1)C(O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.57
LMNA P02545 6/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.46
MAPK1 P28482 3/20 0.46
RAB9A P51151 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
CYP2D6 P10635 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30682789 0.91 LMNA (0.55) CTNNB1LMNACES2CES1SMN1; SMN2
SCHEMBL9284330 0.91 CTNNB1 (0.47) CTNNB1LMNACES2CES1SMN1; SMN2
SCHEMBL10825926 0.84 CTNNB1 (0.62) CTNNB1LMNASMN1; SMN2L3MBTL1MAPK1
SCHEMBL277654 0.81 HPGD (0.56) LMNACES2CES1MAPK1RAB9A
SCHEMBL124171 0.81 LMNA (0.52) LMNACES2CES1L3MBTL1MAPK1
Methoxymethane SCHEMBL5593577 0.80 HPGD (0.55) LMNACES2CES1MAPK1RAB9A
Diphenylether SCHEMBL28786730 0.80 LMNA (0.46) LMNACES2CES1SMN1; SMN2MAPK1
SCHEMBL3362510 0.79 CTNNB1 (0.61) CTNNB1LMNASMN1; SMN2L3MBTL1MAPK1
SCHEMBL10137793 0.79 CTNNB1 (0.61) CTNNB1LMNASMN1; SMN2L3MBTL1RAB9A
SCHEMBL11896596 0.79 LMNA (0.49) LMNACES2CES1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0340216-B1 COMPOSITIONS INCLUDING HERBICIDAL COMBINATIONS OF THE GLYPHOSATE TYPE AND THE PHENOXYBENZOIC TYPE RHONE-POULENC AGROCHIMIE (FR) 1993-05-19 EP claimed
EP-0089538-B1 OPTICALLY ACTIVE DERIVATIVES OF PHENOXY-BENZOIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1985-01-30 EP claimed
WO-2024079245-A1 RIDINILAZOLE FOR TREATING CLOSTRIDIUM DIFFICILE SUMMIT (OXFORD) LIMITED (GB) 2024-04-18 WO disclosed
WO-2023213878-A1 SOLID TABLET DOSAGE FORM OF RIDINILAZOLE SUMMIT (OXFORD) LIMITED (GB) 2023-11-09 WO disclosed
EP-3766527-B1 OSTEOINDUCTIVE BONE IMPLANT AND METHOD FOR ITS IRRADIATION WITH ELECTRON BEAMS WARSAW ORTHOPEDIC INC (US) 2023-09-13 EP disclosed
WO-2023105491-A1 5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEUTICS VRISE THERAPEUTICS, INC. (US) 2023-06-15 WO disclosed
WO-2022153056-A1 PROCESS FOR PURIFYING RIDINILAZOLE SUMMIT (OXFORD) LIMITED (GB) 2022-07-21 WO disclosed
EP-3999502-A1 PROCESS FOR THE PREPARATION OF RIDINILAZOLE AND CRYSTALLINE FORMS THEREOF Summit (Oxford) Limited (GB) 2022-05-25 EP disclosed
EP-3367973-B1 IMPLANTS HAVING A DRUG LOAD OF AN OXYSTEROL AND METHODS OF USE WARSAW ORTHOPEDIC INC (US) 2022-03-23 EP disclosed
US-9987290-B2 Methods for the separation and detection of an oxysterol WARSAW ORTHOPEDIC, INC. (US) 2018-06-05 US disclosed
US-20170273990-A1 METHODS FOR THE SEPARATION AND DETECTION OF AN OXYSTEROL WARSAW ORTHOPEDIC, INC. 2017-09-28 US disclosed
EP-0341607-A2 Anticoagulant peptide alcohols MERRELL DOW PHARMACEUTICALS INC. (US) 1989-11-15 EP disclosed
EP-0340216-A1 COMPOSITIONS INCLUDING HERBICIDAL COMBINATIONS OF THE GLYPHOSATE TYPE AND THE PHENOXYBENZOIC TYPE RHONE-POULENC AGROCHIMIE (FR) 1989-11-08 EP disclosed
EP-0320983-A2 Piperidinyl compounds MERRELL DOW PHARMACEUTICALS INC. (US) 1989-06-21 EP disclosed
WO-1989003641-A1 COMPOSITIONS INCLUDING HERBICIDAL COMBINATIONS OF THE GLYPHOSATE TYPE AND THE PHENOXYBENZOIC TYPE RHONE POULENC AGROCHIMIE (FR) 1989-05-05 WO disclosed
EP-0297534-A2 Castanospermine esters and glycosides MERRELL DOW PHARMACEUTICALS INC. (US) 1989-01-04 EP disclosed
CN-87107479-A Herbicidal composition based on a herbicide of the glyphosate type and on a herbicide of the phenoxybenzoic type and method for controlling weeds using these compositions 1988-08-10 CN disclosed
CN-87107479-A Herbicidal composition based on a herbicide of the glyphosate type and on a herbicide of the phenoxybenzoic type and method for controlling weeds using these compositions 1988-08-10 CN disclosed
EP-0255794-A1 Process for preparing an aromatic acid RHONE-POULENC CHIMIE (FR) 1988-02-10 EP disclosed
US-4242121-A USING A PHENOXYBENZOIC ACID, ITS ESTER OR SALT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170273990-A1 METHODS FOR THE SEPARATION AND DETECTION OF AN OXYSTEROL OSBP2, NR1H3, OSBP CTNNB1 1900/4885LMNA 554/4885CES2 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.