Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597890 | 0.87 | CXCR3 (0.39) | CXCR3CHRM2CHRM3 | |
| SCHEMBL4597761 | 0.84 | KCNJ1 (0.44) | CHRM2CHRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL4596616 | 0.71 | CHRM3 (0.41) | KMT2ACXCR3MEN1ATMCHRM2 | |
| SCHEMBL392531 | 0.66 | HRH3 (0.61) | KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL31093335 | 0.64 | KMT2A (0.59) | KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL7849301 | 0.64 | OPRL1 (0.75) | CHRM2 | |
| SCHEMBL21382443 | 0.63 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5576658 | 0.62 | CCR5 (0.68) | CHRM2CHRM3 | |
| SCHEMBL5576660 | 0.62 | CCR5 (0.68) | CHRM2CHRM3 | |
| SCHEMBL1977991 | 0.62 | KMT2A (0.51) | NPSR1KMT2AMEN1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |