Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 7/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597761 | 0.88 | KCNJ1 (0.44) | CHRM3CHRM2ACHE | |
| SCHEMBL4596620 | 0.87 | NPSR1 (0.38) | CXCR3CHRM3CHRM2 | |
| SCHEMBL4597887 | 0.69 | CHRM3 (0.42) | CXCR3CHRM3CHRM2NCF1 | |
| Benzylamine SCHEMBL27789840 | 0.63 | NCF1 (0.78) | NCF1 | |
| SCHEMBL113089 | 0.61 | NCF1 (0.74) | NCF1 | |
| SCHEMBL8775737 | 0.60 | MEN1 (0.74) | ACHE | |
| SCHEMBL3063295 | 0.60 | CHRM3 (0.59) | CHRM3CHRM2ACHE | |
| SCHEMBL18458216 | 0.59 | SIGMAR1 (0.48) | ACHENCF1 | |
| SCHEMBL8129380 | 0.59 | ALDH1A1 (0.69) | NCF1 | |
| Hydrochloric Acid SCHEMBL7985714 | 0.59 | MEN1 (0.72) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |