Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 10/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230194 | 0.84 | PRKAB2 (0.40) | MEN1KMT2AFFAR1KDM4EALDH1A1 | |
| SCHEMBL4596687 | 0.82 | CA1 (0.40) | FFAR1ALDH1A1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4224655 | 0.81 | LPAR1 (0.39) | LPAR1LPAR5MEN1KMT2AFFAR1 | |
| SCHEMBL6367712 | 0.80 | TDP1 (0.41) | LPAR1LPAR5MEN1KMT2AALDH1A1 | |
| SCHEMBL4230199 | 0.79 | MTNR1A (0.39) | FFAR1MAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4225972 | 0.77 | TDP1 (0.43) | LPAR1LPAR5MEN1KMT2AALDH1A1 | |
| SCHEMBL4596685 | 0.77 | POLB (0.37) | MEN1KMT2AFFAR1KDM4EALDH1A1 | |
| SCHEMBL4226402 | 0.76 | PRKAB2 (0.52) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4596674 | 0.76 | SIRT2 (0.39) | LPAR1LPAR5MEN1KMT2ATDP1 | |
| SCHEMBL4595211 | 0.76 | LMNA (0.38) | LPAR1LPAR5MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |