Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597510 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL4596041 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL4598027 | 0.78 | CHRNA1 (0.32) | — | |
| SCHEMBL4596625 | 0.78 | HTR2C (0.35) | CHRM1 | |
| SCHEMBL4597256 | 0.78 | DRD2 (0.34) | GABRA1GABRG2GABRB3 | |
| SCHEMBL4596506 | 0.78 | DRD2 (0.34) | GABRA1GABRG2GABRB3 | |
| SCHEMBL4625414 | 0.72 | CHRM2 (0.34) | CHRM1 | |
| SCHEMBL4597792 | 0.72 | CHRM2 (0.34) | CHRM1 | |
| SCHEMBL4595948 | 0.72 | BACE1 (0.36) | — | |
| SCHEMBL4415834 | 0.72 | BACE1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |