Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SPIN4 | Q56A73 | 1/20 | 0.33 |
| ▸ | SPIN3 | Q5JUX0 | 1/20 | 0.33 |
| ▸ | SPIN2B | Q9BPZ2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172998 | 0.87 | HTR2A (0.55) | HTR2AHTR2CHTR2BALDH1A1PTGS2 | |
| SCHEMBL13304653 | 0.80 | DHFR (0.51) | DHFRALDH1A1PTGS2NR3C1NR3C2 | |
| SCHEMBL8377139 | 0.78 | PTGS2 (0.60) | DHFRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL12936082 | 0.77 | HTR2A (0.43) | DHFRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL23743654 | 0.76 | ALDH1A1 (0.44) | DHFRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL7088043 | 0.76 | MAPT (0.52) | DHFRALDH1A1PTGS2NR3C1NR3C2 | |
| SCHEMBL13715424 | 0.76 | DHFR (0.41) | DHFRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL5828450 | 0.76 | DHFR (0.41) | DHFRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL111191 | 0.76 | HTR2A (0.69) | HTR2AHTR2CHTR2BPTGS2ACHE | |
| SCHEMBL4597547 | 0.76 | DHFR (0.41) | DHFRHTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150377879-A1 | PEPTOIDS THAT BIND SPECIFIC ANTIGENS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-31 | — | — | US | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150377879-A1 | PEPTOIDS THAT BIND SPECIFIC ANTIGENS | AQP4, AQP3, AQP1 | DHFR 3613/4885HTR2A 4852/4885HTR2C 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.