Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022962 | 0.80 | SIGMAR1 (0.50) | MAPTMEN1KMT2ARECQLTP53 | |
| SCHEMBL5178861 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL7827695 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL4801939 | 0.78 | MAPT (0.45) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL7050263 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL95655 | 0.78 | ENPP2 (0.45) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL4619501 | 0.78 | ALDH1A1 (0.42) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL7050271 | 0.78 | PNMT (0.48) | MAPTALDH1A1SMN1; SMN2KIF11HTR2C | |
| SCHEMBL21208433 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2ARECQLALDH1A1 | |
| SCHEMBL29899606 | 0.78 | ENPP2 (0.45) | MAPTMEN1KMT2ARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907383-A1 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |