SCHEMBL7050263

SCHEMBL7050263

CSc1cccc(C[NH])c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RECQL P46063 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KIF11 P52732 1/20 0.37
KDM4E B2RXH2 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
HTR2C P28335 1/20 0.36
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5022962 0.80 SIGMAR1 (0.50) MAPTMEN1KMT2ATP53RECQL
SCHEMBL1295549 0.79 MAPT (0.43) MAPTMEN1KMT2ATP53POLB
SCHEMBL4597601 0.78 MAPT (0.41) MAPTMEN1KMT2ATP53POLB
SCHEMBL95655 0.78 ENPP2 (0.45) MAPTMEN1KMT2ATP53POLB
SCHEMBL4801939 0.78 MAPT (0.45) MAPTMEN1KMT2ATP53POLB
SCHEMBL7827695 0.78 MAPT (0.41) MAPTMEN1KMT2ATP53POLB
SCHEMBL5178861 0.78 MAPT (0.41) MAPTMEN1KMT2ATP53POLB
SCHEMBL7050271 0.78 PNMT (0.48) MAPTSMN1; SMN2ALDH1A1CYP3A4KIF11
SCHEMBL21208433 0.78 MAPT (0.41) MAPTMEN1KMT2ATP53POLB
SCHEMBL4619501 0.78 ALDH1A1 (0.42) MAPTMEN1KMT2ATP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882715-B1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA CHEMICAL IND CO LTD (JP) 2003-04-23 EP disclosed
US-6339045-B1 CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-01-15 US disclosed
EP-0882715-A1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-09 EP disclosed